- TFFTF
Increasing HR will increase oxygen consumption. CO = HR x Stroke Volume, and SV is proportional to preload, contractility and afterload. DM may cause an autonomic neuropathy, this can give rise to an abnormal Valsalva response. PA catheters assume a continuous column of blood from the catheter tip to the left ventri with no pressure gradients, in mitral stenosis there is a gradient between left atrium and the left ventricle.
FFTTF
In spontaneous ventilation the Mapleson A is extremely efficient and requires a FGF of approximately 70ml/kg/min. The Jackson Rees circuit has an open bag.
FFTTF
Soda lime: 94% calcium hydroxide, 5% sodium hydroxide and 1% potassium hydroxide, with a bit of silica. When fresh, soda lime contains 35% water. At the start of a case circle systems need to be denitrogenated with higher gas flows.
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b) GCS 8. The patient in c) should have any haemodynamic instability resolved even if this requires laparotomy, i.e. ABC before all else. Avoid nasogastric tubes if there is a chance of skull fracture. Tension pneumothoracies should be decompressed as emergencies before an X-ray is taken.
FFFTF
The oculo-cardiac reflex is mediated by the parasympathetic nerve supply via the vagus. Normal IOP is 10-20mmHg. Ketamine and suxamethonium are not ideal agents for use in induction in these cases but sometimes there are no alternatives e.g. patients with a full stomach.
FFFTT
Renal blood supply is 20% of CO. The juxtaglomerular complex produces renin, which via aldosterone promotes K+ excretion in the distal tubule. ANP has an anti renin and anti angiotensin II effect as well as increasing GFR.
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Maintenance fluid is 4/2/1mls/kg/hr respectively for the first, second and subsequent 10kgs of weight. Infants have a higher closing volume that encroaches upon tidal volumes. Alveolar MV is 100-150ml/kg/min due to higher oxygen demand.
TFTFT
Resuscitation fluid bolus is 20ml/kg. Children with pyloric stenosis should have their biochemistry and hydration corrected prior to surgery.
FFTTF
Patients with type II block should have a cardiological referral to consider pacing. Patients with chronic lung conditions are susceptible to hypoventilation and superadded infection, and where available an epidural could be an appropriate form of analgesia. MI patients should avoid all non-urgent surgery for >3months (ideally 6).
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Other causes of EMD include; hypovolaemia, hypothermia, and electrolyte imbalance.
TFFTT
The second dose of adrenaline is 0.1ml/kg of 1:1000, and the resuscitation dose of atropine is 20mcg/kg.
TFFTF
| Isoprenaline: | b1 & b2 |
| Dopamine | 1-2mcg/kg/min: | D receptors |
| Dopamine | 2-10mcg/kg/min: | D & b |
| Dopamine | >10mcg/kg/min: | D, a1 & b |
| Adrenaline: | a1, b1 & b2. |
TTFFT
Ketamine induces dissociative anaesthesia by acting on the NMDA receptor hence its analgesic properties, however it takes greater than one arm brain circulation time to have its full effect. It is not a MH Trigger, unlike suxamethonium and the volatile agents.
TFFFT
Captopril is an angiotensin converting enzyme inhibitor hence it will decrease the amount of aldosterone present in the body (aldosterone normally promotes Na+ retention). ADH will increase total body water not Na+. Fludrocortisone is a synthetic analogue of Aldosterone.
TTFTF
Ach binds to one of the two a subunits of the Ach receptor. The normal resting potential of the NMJ is -90mV.
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The last three are all useful in the secondary management of anaphylaxis but will have no impact on the initial emergency.
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MAOI's interact with opiates causing both excitatory and depressive effects, morphine is thought to be the most safe and pethidine the least. They also interact with indirectly acting sympathomimetic agents producing hypertensive crisis (directly acting drugs are thought to be safer).
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Maximum dose of bupivacaine with adrenaline is the same as without adrenaline i.e. 2mg/kg.
Plain lignocaine can be used up to 3mg/kg.
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The last 3 along with procaine are esters. They have a more frequent incidence of allergy and are metabolised by plasma and liver cholinesterases.
TFTTT
Mivicurium is metabolised by pseudocholinesterases hence deficiency of this enzyme will result in prolonged apnoea.
FTTFT
Nail varnish can absorb coloured light, carboxyhaemoglobin has a similar absorbance to oxyhaemoglobin and methaemoglobin has a similar absorbance to deoxyhaemoglobin hence all interfering with pulse oximetry. Sickle cell and thalassaemia have no bearing on pulse oximetry. ![[Top]](../graphics/top_bult.gif)