Table 5: Intrathecal and epidural opioids for acute pain

Issue 7 (1997) Article 2

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The Management of Postoperative Pain (Continued)

Table 5: Intrathecal and epidural opioids for treatment of acute pain

Drug Single dose
(mg) Onset
(min) Duration of
single dose (h)

Epidural

Morphine 1-6 30 6-24

Pethidine 20-150 5 4-8

Methadone 1-10 10 6-10

Fentanyl 0.025-0.1 5 2-4

Subarachnoid

Morphine 0.1-0.3 15 8-24+

Pethidine 10-30 ? 10-24+

Fentanyl 0.005-0.025 5 3-6